Early, Microcirculatory, Bedside Diagnosis of the Peripheral Atheriosclerotic Obliterating Arteriopathy: Antognetti’s Test.

 From the beginning of the slow evolution of the atheriosclerotic Constitution-Dependent,  Inheritedl Real Risk of atherosclerotic peripheral obliterating disorder, the following Microcirculatory Test revealed to be quick to be applied and reliable from birth in a long clinical experience: Antognetti’s Test, towards the Peripheral Atheriosclerotic Obliterating Arteriopathy (AOPA). In a few words, with a stethoscope the physician observes quickly the Microcirculatory Activation, type 1, associated (1-3) in the downstream tissues.

These events are obviously also observed under the same experimental and clinical conditions in all other tissues. For example, if a stent is malfunctioning downstream the microcirculatory activation is dissociated, type II. Interestingly, identical changes in the local flow-motion are observed in the Impendig Infarct.

In healthy, vasomotility and  vasomotion at rest in the finger-pulp of the foot shows identical, equal to 6 seconds, duration of systole and diastole of the small arteries and arterioles, according to Hammersen, which Prof. Claudio Allegra has perfectly defined “Peripheral Heart”, (= vasomotility), whose behavior is known to be chaotic-deterministic. The fluctuations of the wall of corresponding nutritional capillary are identical, i.e., vasomotility and vasomotion are associated (1-3)

On the contrary, if slight digital pressure (500 dyne/cm.2) is applied, e.g.,  on the common femoral artery in the groin,  simultaneously appears the microcirculatory activation of the  related distal microvessels , whose intensity is correlated with the intensity of arterial jatrogenic occlusion.

In my long personal clinical experience, the Antognetti’s Test proved to be very reliable in both the diagnosis of arterial obstruction and therapeutic monitoring.


1) Sergio Stagnaro.  Introduzione alla Microangiologia Clinica.  10 dicembre 2011. http://www.sisbq.org, http://www.sisbq.org/uploads/5/6/8/7/5687930/mc_intro.pdf

2) Sergio Stagnaro – Marina Neri Stagnaro. Microangiologia Clinica. A cura di Simone Caramel. e-book, http://www.sisbq.org,

http://www.sisbq.org/uploads/5/6/8/7/5687930/microangiologiaclinicasbq2016.pdf 3) Sergio Stagnaro. Diagnosticare l’Arteriopatia Obliterante con un fonendoscopio, secondo Pitagora e Occam. https://sergiostagnaro.wordpress.com/2014/03/02/diagnosticare-larteriopatia-obliterante-con-un-fonendoscopio-secondo-pitagora-e-occam/

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