Archive for March, 2011

Functional decline in older Adults and Co Q10 Deficiency Syndrome.

March 30, 2011

I would like emphasise briefly  the central role of these quantum-biophysical-semeiotic-Constitution-Dependent, Inherited Real Risks also in aging people  disease occurrence.

 

In my opinion, quantum-biophysical-semeiotic diagnosis of Co Q10 deficiency syndrome, I described earlier (1-5),  and the topic of above-cited Letter to Editors Letter to Editors, could be very helpful in risk stratification to predict functional decline in Older Adults.

 

In fact, I have demonstrated that doctors can clinically recognize with the aid of a stethoscope subjects involved by Ubidecarenone deficiency, even initial and symptomless, causing damage of tissues due to the increase levels of free radical (1-5).

 

Moreover, in my 55-long clinical experience, such as diagnosis, made clinically for the first time, proved to be really efficacious and reliable in avoiding dangerous administration of statine to individuals without clinical symptomatology, even involved by ubidecarenone deficiency, notoriously worsened by anti-cholesterolemic drugs.

 

In addition, physicians are able to recognize since birth whatever Constitution-Dependent Inherited quantum-biophysical-semeiotic Real Risk, including oncological, diabetic, and Alzheimer Disease one (5-8), based on microvascular remodelling, characterized by newborn-pathological, type I, subtype a), oncological, and b) aspecific  Endoarteriolar Blocking Devices, which predispose to the related disorders.

 

Finally, only individuals with inherited cerebral quantum-biophysical-semeiotic Inherited Real Risk (5) may be involved by functional decline, like Alzheimer Disease (8), particularly in presence of Co Q10 deficincy syndrome.

 

References

1) Stagnaro-Neri M., Stagnaro S., Carenza di Co Q10 secondaria a terapia ipolipidemmizante diagnosticata con la Percussione Ascoltata. Settimana Italiana di Dietologia, 9-13 Aprile 1991, Merano. Atti, pg. 65. Epat. 37, 17, 1990.

 

2)Stagnaro-Neri M., Stagnaro S., Acidi grassi W-3, scavengers dei radicali liberi e attivatori del ciclo Q della sintesi del Co Q10. Gazz. Med. It. – Arch. Sc. Med. 151, 341, 1992.

 

3) Stagnaro-Neri M., Stagnaro S., Auscultatory Percussion Coenzyme Q deficiency Syndrome. VI Int. Symp., Biomedical and clinical aspects of Coenzyme Q. Rome, January 22.24, 1990,Chairmen K. Folkers, G.L. Littarru, T. Yamagani, Abs., pg. 105.

 

4) Stagnaro-Neri M., Stagnaro S., Sindrome clinica percusso-ascoltatoria da carenza di Co Q10. Medic. Geriatr. XXIV, 239.

 

5) Stagnaro Sergio. Reale Rischio Semeiotico Biofisico. I Dispositivi Endoarteriolari di Blocco neoformati, patologici, tipo I, sottotipo a) oncologico, e b) aspecifico. Ediz. Travel Factory, www.travelfactory.it, Roma, 2009.

 

6) Stagnaro S. Bedside diagnosis of osteoporotic constitution, real risk of inheriting ostoporosis, and finally osteoporosis. Theoretical Biology and Medical Modelling 21 June 2007. http://www.tbiomed.com/content/4/1/23/comments#285569

 

7) Stagnaro S. New bedside way in reducing mortality in diabetic men and women. Ann. Int. Med. . http://www.annals.org/cgi/eletters/0000605-200708070-00167v1

 

8) Stagnaro Sergio. Alzheimer’s Disease Byophysical Semeiotics supports the pathophysiology of Koudinov’s theory.11 January 2002. Clin. Med. & Health Research http://clinmed.netprints.org/cgi/eletters/2001100005v1#9

Renin-Angiotensin Blockade And Kidney Disease Inherited Real Risk.

March 5, 2011

in order to rightly evaluate possible beneficial action of renin-angiotensin blockade in preventing kidney diseases, physicians have to know as well as bedside recognize kidney disease inherited real risk (1-8). In fact, such overlooked congenital real risk represents the “condition sine qua non” of kidney disorder, different in nature.

As a consequence, renin-angiotensin blockade must be happen in individual properly enrolled, because kidney disorders will never occur in absence of renal inherited real risk. In addition, it is generally admitted that early diagnosis is the conditio sine qua non of the best therapeutic results. Unfortunately, renal disorders, including cancer, and other less common disorder of urinary tract are mainly recognized later, since for years or decades they are silent from the clinical view-point. The following easy manoeuvre plays a central role also in recognizing renal inherited real risk. In health, “light-moderate” persisting stimulation by cutaneous pintching of renal trigger-points, i.e., VIII-X thoracic dermatomeres (= lateral abdominal quadrants), after exact 8 sec. latency time, brings about aspecific gastric reflex: in the stomach, both fundus and body dilate, while antral-pyloric region contracts: http://www.semeioticabiofisica.it. Reflex duration lasts LESS than 4 sec.: such as parameter value, paralleling local Microcirculatory Functional Reserve, plays a paramount role in bedside excluding Renal Cancer, as well as all other kidney diseases, even in its first stage of inherited real risk, characterized by newborn-pathological, type I, subtype a) oncological, and b) aspecific Endoarteriolar Blocking Devices (6-8). On the contrary, in individual involved by Inherited oncological or aspecific Kidney Real Risk, including urinary way cancer, the identical stimulation causes aspecific gastric reflex, showing normal latency time (NN = 8 sec.), BUT its duration is 4 sec. or more, i.e. pathological.

Really, these two parameter values are inversely and respectively directly related to the seriousness of underlying disorders. Immediately there after, in oncological real risk only, one observes tonic Gastric Contraction, typical of tumoural lesion: Pollio’s Sign.

Interestingly, when renal trigger-points stimulation is “intense”, due to non local realm of biological system (8-10), all components of urinary tract are “simultaneously” stimulated: in health, reflex latency time raises from 8 sec. to 16 sec., because locally free energy is increased, due to type I, associated, microcirculatory activation (3-7). Interestingly, in subject involved by both Oncological Terrain and Inherited Oncological Real Risk in whatever part of urinary system (kidney, urinary bladder, and prostate), “intense” stimulation of a UNIQUE trigger-point causes “simultaneously” intense aspecific gastric reflex, immediately followed by great tonic Gastric Contraction: Pollio’s Sign, which surely will play a paramount role in RC as well as in urinary tract malignancies primary prevention. Subsequently, physicians will localized tumoural lesion with the aid of a lot of biophysical-semeiotic signs (1-7).

 

Pollio’s Sign. In memory of my dear friend, Fabrizio Pollio MD, brilliant gynaecologist surgeon, dead at age of 34 years for renal cancer.

 

References.

1) Stagnaro Sergio. (7 February 2008). Bedside diagnosing prostate cancer inherited oncological real risk and its therapy. Annals of Internal Medicine. http://www.annals.org/cgi/eletters/0000605-200803180-00209v1

2) Stagnaro Sergio. Oncogenesis is possible exclusively in individuals Oncological Terrain-positive. http://www.thescientist.com 2007. http://www.the-scientist.com/blog/print/53498/

3) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeiotica Biofisica. Il Terreno Oncologico. Ed. Travel Factory, Roma, 2004. http://www.travelfactory.it

4) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it/

5) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine. Travel Factory, Roma, 2004. http://www.travelfactory.it/

6) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it

7) Stagnaro Sergio. Oncological Terrain and Inherited Oncological Real Risk: New Way in Malignancy Primary Prevention and early Diagnosis. International Seminars in Surgical Oncology, 2007. http://www.issoonline.com/content/4/1/25/comments#290565

8) Stagnaro Sergio. Newborn-pathological Endoarteriolar Blocking Devices in Diabetic and Dislipidaemic Constitution and Diabetes Primary Prevention. The Lancet. March 06 2007. http://www.thelancet.com/journals/lancet/article/PIIS0140673607603316/comments?totalcomments=1

9) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica: Realtà non-locale in Biologia. Dicembre 2007, http://www.ilpungolo.com, http://www.ilpungolo.com/leggi-tutto.asp?IDS=13&NWS=NWS5217

10) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica Quantistica. http://www.ilpungolo.com/leggi-tutto.asp?IDS=13&NWS=NWS5243

11) Stagnaro Sergio. Esperimento di Lory e Crisi dei Fondamenti della Medicina Occidentale. http://www.ilpungolo.com. 17 Febbraio 2008 http://www.ilpungolo.com/leggi-tutto.asp?NWS=NWS5387&IDS=13

Renin-Angiotensin Blockade And Kidney Disease Inherited Real Risk.

March 5, 2011

In order to rightly evaluate possible beneficial action of renin-angiotensin blockade in preventing kidney diseases, physicians have to know as well as bedside recognize kidney disease inherited real risk (1-8). In fact, such overlooked congenital real risk represents the “condition sine qua non” of kidney disorder, different in nature.
As a consequence, renin-angiotensin blockade must be happen in individual properly enrolled, because kidney disorders will never occur in absence of renal inherited real risk. In addition, it is generally admitted that early diagnosis is the conditio sine qua non of the best therapeutic results. Unfortunately, renal disorders, including cancer, and other less common disorder of urinary tract are mainly recognized later, since for years or decades they are silent from the clinical view-point. The following easy manoeuvre plays a central role also in recognizing renal inherited real risk. In health, “light-moderate” persisting stimulation by cutaneous pintching of renal trigger-points, i.e., VIII-X thoracic dermatomeres (= lateral abdominal quadrants), after exact 8 sec. latency time, brings about aspecific gastric reflex: in the stomach, both fundus and body dilate, while antral-pyloric region contracts: http://www.semeioticabiofisica.it. Reflex duration lasts LESS than 4 sec.: such as parameter value, paralleling local Microcirculatory Functional Reserve, plays a paramount role in bedside excluding Renal Cancer, as well as all other kidney diseases, even in its first stage of inherited real risk, characterized by newborn-pathological, type I, subtype a) oncological, and b) aspecific Endoarteriolar Blocking Devices (6-8). On the contrary, in individual involved by Inherited oncological or aspecific Kidney Real Risk, including urinary way cancer, the identical stimulation causes aspecific gastric reflex, showing normal latency time (NN = 8 sec.), BUT its duration is 4 sec. or more, i.e. pathological.
Really, these two parameter values are inversely and respectively directly related to the seriousness of underlying disorders. Immediately there after, in oncological real risk only, one observes tonic Gastric Contraction, typical of tumoural lesion: Pollio’s Sign.
Interestingly, when renal trigger-points stimulation is “intense”, due to non local realm of biological system (8-10), all components of urinary tract are “simultaneously” stimulated: in health, reflex latency time raises from 8 sec. to 16 sec., because locally free energy is increased, due to type I, associated, microcirculatory activation (3-7). Interestingly, in subject involved by both Oncological Terrain and Inherited Oncological Real Risk in whatever part of urinary system (kidney, urinary bladder, and prostate), “intense” stimulation of a UNIQUE trigger-point causes “simultaneously” intense aspecific gastric reflex, immediately followed by great tonic Gastric Contraction: Pollio’s Sign, which surely will play a paramount role in RC as well as in urinary tract malignancies primary prevention. Subsequently, physicians will localized tumoural lesion with the aid of a lot of biophysical-semeiotic signs (1-7).

Pollio’s Sign. In memory of my dear friend, Fabrizio Pollio MD, brilliant gynaecologist surgeon, dead at age of 34 years for renal cancer.

References.
1) Stagnaro Sergio. (7 February 2008). Bedside diagnosing prostate cancer inherited oncological real risk and its therapy. Annals of Internal Medicine. http://www.annals.org/cgi/eletters/0000605-200803180-00209v1
2) Stagnaro Sergio. Oncogenesis is possible exclusively in individuals Oncological Terrain-positive. http://www.thescientist.com 2007. http://www.the-scientist.com/blog/print/53498/
3) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeiotica Biofisica. Il Terreno Oncologico. Ed. Travel Factory, Roma, 2004. http://www.travelfactory.it
4) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it/
5) Stagnaro S., Stagnaro-Neri M., Le Costituzioni Semeiotico-Biofisiche.Strumento clinico fondamentale per la prevenzione primaria e la definizione della Single Patient Based Medicine. Travel Factory, Roma, 2004. http://www.travelfactory.it/
6) Stagnaro S., Stagnaro-Neri M., La Melatonina nella Terapia del Terreno Oncologico e del “Reale Rischio” Oncologico. Travel Factory, Roma, 2004. http://www.travelfactory.it
7) Stagnaro Sergio. Oncological Terrain and Inherited Oncological Real Risk: New Way in Malignancy Primary Prevention and early Diagnosis. International Seminars in Surgical Oncology, 2007. http://www.issoonline.com/content/4/1/25/comments#290565
8) Stagnaro Sergio. Newborn-pathological Endoarteriolar Blocking Devices in Diabetic and Dislipidaemic Constitution and Diabetes Primary Prevention. The Lancet. March 06 2007. http://www.thelancet.com/journals/lancet/article/PIIS0140673607603316/comments?totalcomments=1
9) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica: Realtà non-locale in Biologia. Dicembre 2007, http://www.ilpungolo.com, http://www.ilpungolo.com/leggi-tutto.asp?IDS=13&NWS=NWS5217
10) Stagnaro Sergio e Paolo Manzelli. Semeiotica Biofisica Quantistica. http://www.ilpungolo.com/leggi-tutto.asp?IDS=13&NWS=NWS5243
11) Stagnaro Sergio. Esperimento di Lory e Crisi dei Fondamenti della Medicina Occidentale. http://www.ilpungolo.com. 17 Febbraio 2008 http://www.ilpungolo.com/leggi-tutto.asp?NWS=NWS5387&IDS=13